Rotating Night Shift Work and Risk of Ovarian Cancer

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Rotating night shift work and risk of ovarian cancer.

BACKGROUND Night shift work has been associated with higher risks of breast and endometrial cancer, but few studies have evaluated associations with other reproductive cancers. METHODS We examined the association between rotating night shift work and risk of ovarian cancer during 20 years of follow-up in 181,548 women participating in two large cohort studies, the Nurses' Health Study (NHS) a...

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Rotating night shift work and the risk of ischemic stroke.

Rotating night shift work disrupts circadian rhythms and is associated with coronary heart disease. The relation between rotating night shift work and ischemic stroke is unclear. The Nurses' Health Study, an ongoing cohort study of registered female nurses, assessed in 1988 the total number of years the nurses had worked rotating night shifts. The majority (69%) of stroke outcomes from 1988 to ...

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Rotating night shift work and mammographic density.

BACKGROUND An increased risk of breast cancer has been observed in night shift workers. Exposure to artificial light at night and disruption of the endogenous circadian rhythm with suppression of the melatonin synthesis have been suggested mechanisms. We investigated the hypothesis that rotating night shift work is associated with mammographic density. METHODS We conducted a cross-sectional s...

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Shift work, night work, and the risk of prostate cancer

BACKGROUND Epidemiology studies suggested that shift work or night work may be linked to prostate cancer (PCa); the relationship, however, remains controversy. METHODS PubMed, ScienceDirect, and Embase (Ovid) databases were searched before (started from the building of the databases) February 4, 2017 for eligible cohort studies. We pooled the evidence included by a random- or fixed-effect mod...

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Night shift work and the risk of endometrial cancer.

Melatonin has several oncostatic properties, including possible anti-estrogenic and anti-aromatase activity, and seems to be linked with fat metabolism. Night workers have lower levels of melatonin, which may predispose them to develop cancer. Endometrial cancer risk is influenced significantly by hormonal and metabolic factors; therefore, we hypothesize that night workers may have an increased...

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ژورنال

عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention

سال: 2011

ISSN: 1055-9965,1538-7755

DOI: 10.1158/1055-9965.epi-11-0138